名稱(chēng) | PDGFRA D842V/BaF3 |
型號(hào) | CBP73238 |
報(bào)價(jià) | ![]() |
特點(diǎn) | PDGFRA D842V/BaF3,母細(xì)胞:BaF3,凍存條件:90% FBS+10% DMSO |
產(chǎn)品搜索
產(chǎn)品分類(lèi)
相關(guān)文章
- 證據(jù):鍛煉或許并不是控制體重的關(guān)鍵
- CD74-ROS1的藥靶模型+DNARNA標(biāo)準(zhǔn)品+ddPCR試劑盒
- 心衰治療靶點(diǎn):BNP/NPR1
- 腫瘤細(xì)胞能無(wú)限分裂的原因有哪些?
- 黃金賽道——CDH17靶點(diǎn)
- 腫瘤細(xì)胞內(nèi)的膠原蛋白有哪些作用?
- 【新品上線(xiàn)】一種安全高效的中和抗體體外篩選模型
- VKORC1基因多態(tài)性用藥指導(dǎo)標(biāo)準(zhǔn)品
- 上海細(xì)胞中心人員需了解的專(zhuān)業(yè)“術(shù)語(yǔ)”
- 細(xì)胞株購(gòu)買(mǎi)為何比較看重生物等級(jí)?
聯(lián)系我們
電話(huà):4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73238PDGFRA D842V/BaF3

- 詳細(xì)內(nèi)容
CBP73238 | |
I. Introduction | |
Cell Line Name: | PDGFRA D842V/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
PDGFRA D842V lies within the protein kinase domain of the Pdgfra protein (UniProt.org). D842V results in ligand-independent phosphorylation of Pdgfra, activation of downstream signaling, and is transforming in culture (PMID: 22745105, PMID: 23752188, PMID: 29533785, PMID: 30253204) and confers resistance to PDGFRA inhibitors (PMID: 30389923, PMID: 18955458). | |
III. Representative Data | |
1.PDGFRA D842V/BaF3 | |
2.Sanger of PDGFRA D842V/BaF3 Figure 2. PDGFRA D842V/BaF3 D842V | |
3. Anti-proliferation assay | |
Figure 3. CTG Proliferation Assay of BaF3 PDGFRA D842V Cells(C6). |