| 名稱 | CD86/CHO |
| 型號(hào) | CBP74070 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | CD86/CHO，凍存條件：90% FBS+10% DMSO |
產(chǎn)品搜索
相關(guān)文章
- IgE：過(guò)敏與免疫的“雙面分子”
- 熱門CTLA4&PD1/L1雙靶點(diǎn)抗體活性檢測(cè)細(xì)胞模型
- 【靶點(diǎn)模型】AKT基因的藥物開(kāi)發(fā)
- 【產(chǎn)品推介】腫瘤融合基因檢測(cè)及靶向治療
- 【連載-企業(yè)參考品】 神經(jīng)膠質(zhì)瘤的診斷參考品的選擇
- ADCC/ADCP細(xì)胞篩選模型
- Cell Rep：發(fā)現(xiàn)治療乳腺癌轉(zhuǎn)移的重要新靶標(biāo)！
- 腫瘤細(xì)胞分裂“制動(dòng)系統(tǒng)”相關(guān)基因分析
- NK細(xì)胞激活總開(kāi)關(guān)：NKG2D
- 【靶點(diǎn)模型+診斷質(zhì)控】FLT3-ITD的藥物開(kāi)發(fā)和診斷
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74070CD86/CHO
- 詳細(xì)內(nèi)容
| CBP74070 | |
| I. Background | |
| B7-2 (CD86) signaling through CTLA4 (CD152) has been shown to inhibit T- cell activation. This co-inhibitory pathway can be overactive in many tumors, enabling cancers to escape the host’s immune system. CTLA4-blocking antibodies, including Ipilimumab (Yervoy) and Tremelimumab, have shown clinical efficacy in treating cancer. | |
| II. Description | |
Recombinant CHO cells constitutively expressing human CD86. | |
| III. Introduction | |
| Host Cell: | CHO |
| Expressed gene: | CD86 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Synonym(s): | T-lymphocyte activation antigen CD86, B7.2, FUN-1, B70, BU63, CD86, B72 |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+500ug/ml hygromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Ligand of CD28&Binding Assay,FACS |
| IV. Description of Host Cell Line | |
| Organism: | Cricetulus griseus, hamster, Chinese |
| Tissue: | Ovary |
| Disease: | Hamster Chinese ovary |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| Ⅴ. Representative Data | |
Figure 1. Recombinant CHO cells expressing human CD86. | |
會(huì)員_a.png)