| 名稱 | BRAF p.G469R Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10236 |
| 報(bào)價(jià) | 900 |
| 特點(diǎn) | BRAF p.G469R Reference Standard |
產(chǎn)品搜索
相關(guān)文章
- 【靶點(diǎn)模型+診斷質(zhì)控】BCR-ABL1的藥物開發(fā)和診斷
- IL-21藥篩細(xì)胞模型
- 剖析正常細(xì)胞是如何成長(zhǎng)為腫瘤細(xì)胞的
- 增強(qiáng)腫瘤免疫療法新靶點(diǎn)：ADORA2B（腺苷A2B受體）
- Nature：繞過Ras激酶“不可成藥性”的抗癌新思路
- OX40&PD-1/L1雙免疫檢查點(diǎn)細(xì)胞篩選模型
- FGFR2融合靶向藥物細(xì)胞篩選模型
- 科學(xué)家有望利用對(duì)療法敏感性的癌細(xì)胞來清除耐藥性癌細(xì)胞
- IDH基因診斷標(biāo)準(zhǔn)品
- 細(xì)胞株的STR鑒定技術(shù)分享
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10236BRAF p.G469R Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10236 | |
| Format | Genomic DNA |
| Description | BRAF G469R is a hotspot mutation within the protein kinase domain of the Braf protein (UniProt.org). G469R demonstrates intermediate BRAF kinase activity (PMID: 28783719) and results in constitutive ERK activation in cell culture (PMID: 24920063), and in one of two cell lines leads to increased cell proliferation and cell viability compared to wild-type Braf (PMID: 29533785), and is therefore predicted to confer a gain of function to the Braf protein. |
| Technical Data | |
| DNA Change | c.1405G>A |
| AA Change | p.G469R |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Transcript | ENST00000288602 |
| Cosmic ID | COSM457 |
| Chr position(GRCh37) | chr7:140481403 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
會(huì)員_a.png)