名稱(chēng) | FGFR3 p.SP400fs Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10504 |
報(bào)價(jià) | ![]() |
特點(diǎn) | FGFR3 p.SP400fs Reference Standard |
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電話(huà):4008750250
號(hào)碼:
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地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10504FGFR3 p.SP400fs Reference Standard 標(biāo)準(zhǔn)品

- 詳細(xì)內(nèi)容
CBP10504 | |
Format | Genomic DNA |
Description | FGFR3, fibroblast growth factor receptor 3, is a receptor tyrosine kinase activated upon binding of the FGF ligand, which activates RAS-MAPK and PI3K-AKT pathways (PMID: 22508544). Altered function of FGFR3 in cancer may lead to increased cell proliferation and decreased apoptosis (PMID: 22508544) and mutations and fusions are commonly observed in bladder cancer (PMID: 30975452, PMID: 23175443). |
Technical Data | |
DNA Change | c.1200insCC |
AA Change | p.SP400fs |
Mutation type | |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | N/A |
Cosmic ID | N/A |
Chr position(GRCh37) | chr4:1806180 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |