| 名稱(chēng) | HRAS p.G12V Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10289 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | HRAS p.G12V Reference Standard |
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10289HRAS p.G12V Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
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CBP10289 | |
| Format | Genomic DNA |
| Description | HRAS G12V is hotspot mutation that lies within a GTP nucleotide binding region of the Hras protein (UniProt.org). G12V results in decreased Hras GTPase activity, loss of response to GTPase-activating proteins, leading to activation of downstream signaling pathways, and transformation of cultured cells (PMID: 24224811, PMID: 21850009, PMID: 6330729). |
| Technical Data | |
| DNA Change | c.35G>T |
| AA Change | p.G12V |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000397596 |
| Cosmic ID | COSM483 |
| Chr position(GRCh37) | chr11:534288 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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